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The Match Up: CBDA vs CBD

CBDA is considered the natural form of CBD, that being it’s the compound most present in plants. But, what exactly are the differences? 


As we mentioned, CBDA is the naturally occurring molecule in plants. CBDA is made by the plant through complex chemical reaction stimulated by the plants need for natural immunity and protection against invaders such as pests and viruses. 


CBDA contains a special chemical group called a “carboxylic acid” group.  This special group allows for the plant (and us) to use the compound more easily against viruses, damage, and pests. 


Several peer reviewed research studies suggest that CBDA is more available in the human body compared to CBD. The NIDA did a study suggesting that ingesting CBDA leads to over 4 times the amount of absorptions when compared to CBD (cite study). This greater absorption allows the body to more readily use CBDA and allows us to ingest smaller amounts that are available in consumer products. 


While CBD only appears to be most active as the traditional ESC receptors CB1 and CB2, CBDA appears to be active at many other receptor sites throughout the body including the same receptors as Arnica oil, Turmeric, and Capsaicin.  These receptors include: vanillnaoid families (TRPV/TRPA), peroxisome proliferator-activated receptors (PPARs), and serotonin (5-HT1A).  

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